ISSN 1662-4009 (online)

ey0019.14-2 | Basics of human biology | ESPEYB19

14.2. Cholesterol is required for transcriptional repression by BASP1

Loats Amy E , Carrera Samantha , Fleming Anna F , Roberts Abigail R E , Sherrard Alice , Toska Eneda , Moorhouse Alexander J , Medler Kathryn F , Roberts Stefan G E

Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2101671118. doi: 10.1073/pnas.2101671118Brief Summary: This cell model study shows that cholesterol is essential for the transcriptional repressor and cell differentiation activities of brain acid soluble protein 1 (BASP1).Cholesterol biology covers a spectrum of functions spanning from the biosynthesis of Vitamin D, bile a...